Konsentrasi Basic Fibroblast Growth Factor (bFGF) dan Transforming Growth Factor-Beta 1 (TGF-β1) pada Penyembuhan Luka Kulit Tikus
DOI:
10.25047/j-kes.v11i1.337Issue:
Vol. 11 No. 1 (2023): AprilArticles
Downloads
How to Cite
Downloads
Abstract
Acceleration of wound healing is now becomes a trend center for many researcher to explore various herbs which are containing compounds that can affecting some factors involved in wound healing process. Growth factors is one of the marker that can be analyzed whether a certain herb can accelerate wound healing. To better understand how a certain herb invloved in the acceleration of wound healing, a growth factors-study was conducted. Archived skin tissue of rats from previous study (unpublished) which were been treated with Anredera cordifolia (Binahong) extract were used, and subjected to enzyme-linked immunosorbent assay (ELISA) to quantify bFGF and TGF-β1. The results obtained was then analyzed descriptively between the control group (Binahong-untreated) and treatment group (Binahong-treated). The ELISA results showed no siginificant difference of bFGF and TGF-β1 concentration between control group (Binahong-untreated) and treatment group (Binahong-treated). However, the concentration of bFGF dan TGF-β1 on day 14 were decreasing compared with those concentration on day 7, assumed the wound healing phase has already entering the next phase where the production of bFGF and TGF-β1 have been replaced with other growth factors involved in wound healing process
Author Biography
Anggi Puspa Nur Hidayati, Pusat Penelitian Sel Punca Universitas YARSI
License
Copyright (c) 2023 Anggi Puspa Nur Hidayati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish in this journal agree to the following terms:
1. Copyright belongs to the medical journal as a publication
2. The author retains copyright and grants the journal rights to the first publication carried out simultaneously under a Creative Commons Attribution License which allows others to share the work with an acknowledgment of the author's work and initial publication in this journal.
3. Authors may enter into separate additional contractual arrangements for the non-exclusive distribution of the work (eg sending it to an institutional repository or publishing it in a book) with acknowledgment of initial publication in this journal.
4. Authors are permitted and encouraged to post work online (eg in institutional repositories or on their websites) before and during the submission process, as before and larger citations of published work (see Effects of Open Access).
Selengkapnya tentang teks sumber ini
